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Febuxostat

Uses: Febuxostat is in a class of medications called xanthine oxidase inhibitors. It works by decreasing the amount of uric acid that is made in the body. Febuxostat is used to prevent gout.
Identifiers
CAS No:
[144060-53-7]
BRN No:
-
UN No:
-
Properties
Molecular Formula:
C16H16N2O3S
Molecular Weight:
316.37 g/mol

Specifications

Sr. No. Test Limits
1 Description Off –white to pale yellow powder.
2 Solubility Soluble in Tetrahydrofuran, and in Ethanol
3 Identification
a) By FTIR The Infrared absorption spectrum of the
sample should be concordant with that of
the standard.
b) By HPLC The retention time of the principal peak in
sample preparation should correspond with
that obtained in standard preparation.
4 Water Content by KF (%, w/w) Not more than 1.0
5 Sulphated Ash (%, w/w) Not more than 0.1
6 Heavy Metals (ppm) Not more than 20
7 Related Substances by HPLC (%, w/w)
Single maximum impurity
Total impurities

Not more than 0.5
Not more than 1.0
8 Assay by HPLC(%, w/w)
(As
“C16H16N2O3S”
, on anhydrous basis)
Between 98.0 to 102.0
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